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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCE
All Species:
30.3
Human Site:
T643
Identified Species:
74.07
UniProt:
Q02156
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02156
NP_005391.1
737
83674
T643
S
I
L
K
A
F
M
T
K
N
P
H
K
R
L
Chimpanzee
Pan troglodytes
XP_001168420
683
77824
T590
G
I
L
K
S
F
M
T
K
N
P
T
M
R
L
Rhesus Macaque
Macaca mulatta
XP_001112738
736
83540
T642
S
I
L
K
A
F
M
T
K
N
P
H
K
R
L
Dog
Lupus familis
XP_851861
737
83557
T643
S
I
L
K
A
F
M
T
K
N
P
H
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P16054
737
83542
T643
S
I
L
K
A
F
M
T
K
N
P
H
K
R
L
Rat
Rattus norvegicus
P09216
737
83460
T643
S
I
L
K
A
F
M
T
K
N
P
H
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419464
743
84532
T649
S
I
L
K
A
F
M
T
K
N
P
N
K
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
D520
F
F
R
N
V
D
W
D
L
M
E
Q
K
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
D550
Q
R
L
G
C
T
G
D
E
N
E
I
R
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
T613
N
I
L
K
A
F
M
T
K
N
A
G
K
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
99.7
98.9
N.A.
97.9
98
N.A.
N.A.
94.6
N.A.
36
N.A.
52.7
N.A.
58.6
N.A.
Protein Similarity:
100
75.8
99.8
99.3
N.A.
99.4
99.3
N.A.
N.A.
96.7
N.A.
51.4
N.A.
66.2
N.A.
74.7
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
6.6
N.A.
13.3
N.A.
80
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
20
N.A.
33.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
20
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
20
0
0
0
0
% E
% Phe:
10
10
0
0
0
80
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
10
% H
% Ile:
0
80
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
80
0
0
0
0
80
0
0
0
80
10
0
% K
% Leu:
0
0
90
0
0
0
0
0
10
0
0
0
0
0
80
% L
% Met:
0
0
0
0
0
0
80
0
0
10
0
0
10
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
90
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
10
80
0
% R
% Ser:
60
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
80
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _